Mouse Osteoactivin/GPNMB PicoKine ELISA Kit

Mouse Osteoactivin/GPNMB PicoKine ELISA Kit 

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Osteoactivin/GPNMB ELISA Kit (Mouse) (OKBB00605)

OKBB00605 96 Wells
EUR 606
Description: Description of target: Transmembrane glycoprotein NMB is a protein that is encoded by the GPNMB gene. In osteoblast progenitor cells, GPNMB works as a positive regulator of osteoblast differentiation during later stages of matrix maturation and mineralization that is mediated at least in part by BMP-2 in a SMAD1 dependent manner to promote osteoblast differentiation. GPNMB can enhance the repairing process in bone fracture, demonstrated by its high expression during chondrogenesis (soft callus) and osteogenesis (hard callus) compared to the intact femurs that is why Osteoactivin (OA) could be a novel therapeutic agent used to treat generalized osteoporosis or localized osteopenia during fracture repair by stimulating bone growth and regeneration. Similarly, GPNMB expression increases during osteoclast differentiation and it is functionally implicated in this process, possibly by promoting the fusion of osteoclast progenitor cells.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

ELISA kit for Mouse GPNMB/Osteoactivin

EK5608 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse GPNMB/Osteoactivin in samples from serum, plasma, tissue homogenates and other biological fluids.

Nori® Human Osteoactivin/GPNMB ELISA Kit

GR106390 96-well
EUR 832

ELISA kit for Human GPNMB/Osteoactivin

EK5557 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human GPNMB/Osteoactivin in samples from serum, plasma, tissue homogenates and other biological fluids.

GPNMB/Osteoactivin ELISA Kit (Human) (OKBB00561)

OKBB00561 96 Wells
EUR 606
Description: Description of target: Transmembrane glycoprotein NMB is a protein that in humans is encoded by the GPNMB gene. In osteoblast progenitor cells, GPNMB works as a positive regulator of osteoblast differentiation during later stages of matrix maturation and mineralization that is mediated at least in part by BMP-2 in a SMAD1 dependent manner to promote osteoblast differentiation. GPNMB can enhance the repairing process in bone fracture, demonstrated by its high expression during chondrogenesis (soft callus) and osteogenesis (hard callus) compared to the intact femurs that is why Osteoactivin (OA) could be a novel therapeutic agent used to treat generalized osteoporosis or localized osteopenia during fracture repair by stimulating bone growth and regeneration. Similarly, GPNMB expression increases during osteoclast differentiation and it is functionally implicated in this process, possibly by promoting the fusion of osteoclast progenitor cells.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Nori® Human Osteoactivin/GPNMB ELISA Kit (2 plates)

GR106390-2 2 x 96-well
EUR 461

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-10ug 10ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-50ug 50ug
EUR 327.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Human CellExp? Osteoactivin / GPNMB, human recombinant

7513-10 each
EUR 294

Human Osteoactivin ELISA KIT

DEIA7058 96T
EUR 1075.2
Description: The Human Osteoactivin ELISA KIT is suitable for the quantitative determination of human soluble Osteoactivin/GPNMB concentrations in cell culture supernates, serum, and plasma.

Osteoactivin Recombinant Protein

91-449 0.05 mg
EUR 556.8
Description: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.

Osteoactivin Recombinant Protein

96-368 0.1 mg
EUR 619.8
Description: Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

Human Osteoactivin Protein (Ala 22-Pro 486) [His]

VAng-2623Lsx-100g 100 µg
EUR 918
Description: Human Osteoactivin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH32783)

Human Osteoactivin Protein (Ala 22-Pro 486) [His]

VAng-2623Lsx-1mg 1 mg
EUR 5338.8
Description: Human Osteoactivin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH32783)

Mouse Osteoadherin PicoKine ELISA Kit

EK2018 96 wells
EUR 510
Description: For quantitative detection of mouse Osteoadherin in cell culture supernates, serum and plasma (heparin, EDTA).

Human Osteoadherin PicoKine ELISA Kit

EK2017 96 wells
EUR 510
Description: For quantitative detection of human Osteoadherin in cell culture supernates, serum and plasma (heparin, EDTA).

Mouse OPG (TNFRSF11B) / Osteoprotegerin PicoKine™ Fast ELISA Kit

FEK0481 96 wells
EUR 583.2
Description: The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Mouse Osteoprotegerin/TNFRSF11B with <5pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernates, serum and plasma(EDTA). This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Osteoprotegerin/TNFRSF11B tissue specificity: Highly expressed in liver, lung, stomach, intestines and calvaria. Highly expressed in decidua and placenta, and in embryo.

Mouse MPO PicoKine ELISA Kit

EK0943 96 wells
EUR 510
Description: For quantitative detection of mouse MPO in cell culture supernates, cell lysates, serum and plasma(heparin, EDTA).

Mouse CRP PicoKine ELISA Kit

EK0977 96 wells
EUR 510
Description: For quantitative detection of mouse CRP in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse SAA PicoKine ELISA Kit

EK1190 96 wells
EUR 510
Description: For quantitative detection of mouse SAA in cell culture supernates, serum, plasma(heparin, EDTA) and urine.

Mouse HGF PicoKine ELISA Kit

EK1217 96 wells
EUR 510
Description: For quantitative detection of mouse HGF in cell culture supernates, serum and plasma(EDTA, citrate).

Mouse Osteoactivin/GPNMB PicoKine ELISA Kit