Mouse Osteoactivin/GPNMB PicoKine ELISA Kit

Mouse Osteoactivin/GPNMB PicoKine ELISA Kit 

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GPNMB/Osteoactivin ELISA Kit (Human) (OKBB00561)

OKBB00561 96 Wells
EUR 505
Description: Description of target: Transmembrane glycoprotein NMB is a protein that in humans is encoded by the GPNMB gene. In osteoblast progenitor cells, GPNMB works as a positive regulator of osteoblast differentiation during later stages of matrix maturation and mineralization that is mediated at least in part by BMP-2 in a SMAD1 dependent manner to promote osteoblast differentiation. GPNMB can enhance the repairing process in bone fracture, demonstrated by its high expression during chondrogenesis (soft callus) and osteogenesis (hard callus) compared to the intact femurs that is why Osteoactivin (OA) could be a novel therapeutic agent used to treat generalized osteoporosis or localized osteopenia during fracture repair by stimulating bone growth and regeneration. Similarly, GPNMB expression increases during osteoclast differentiation and it is functionally implicated in this process, possibly by promoting the fusion of osteoclast progenitor cells.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

ELISA kit for Human GPNMB/Osteoactivin

EK5557 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human GPNMB/Osteoactivin in samples from serum, plasma, tissue homogenates and other biological fluids.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Osteoactivin/GPNMB (C-6His)

C497-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Human CellExp? Osteoactivin / GPNMB, human recombinant

7513-10
EUR 245

Human Osteoactivin ELISA KIT

DEIA7058 96T
EUR 896
Description: The Human Osteoactivin ELISA KIT is suitable for the quantitative determination of human soluble Osteoactivin/GPNMB concentrations in cell culture supernates, serum, and plasma.

Osteoactivin Recombinant Protein

96-368 0.1 mg
EUR 516.5
Description: Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

Osteoactivin Recombinant Protein

91-449 0.05 mg
EUR 464
Description: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.

GPNMB ELISA KIT|Human

EF005385 96 Tests
EUR 689

Mouse VEGF PicoKine ELISA Kit

EK0541 96 wells
EUR 425
Description: For quantitative detection of mouse VEGF in cell culture supernates, serum and plasma(heparin, EDTA, citrate).

Mouse ACE PicoKine ELISA Kit

EK0558 96 wells
EUR 425
Description: For quantitative detection of mouse ACE in cell culture supernates, serum and plasma(heparin).

Mouse CD30 PicoKine ELISA Kit

EK0570 96 wells
EUR 425
Description: For quantitative detection of mouse CD30 in cell culture supernates and serum.

Mouse CD30L PicoKine ELISA Kit

EK0572 96 wells
EUR 436
Description: For quantitative detection of mouse CD30L in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse CD40L PicoKine ELISA Kit

EK0574 96 wells
EUR 455
Description: For quantitative detection of mouse CD40L in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse LIF PicoKine ELISA Kit

EK0580 96 wells
EUR 425
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA).

Mouse Resistin PicoKine ELISA Kit

EK0582 96 wells
EUR 456
Description: For quantitative detection of mouse Resistin in cell culture supernates, serum and plasma(heparin).

Mouse Prolactin PicoKine ELISA Kit

EK0594 96 wells
EUR 455
Description: For quantitative detection of mouse Prolactin in cell culture supernates, serum and plasma(heparin, citrate).

Mouse Adiponectin PicoKine ELISA Kit

EK0596 96 wells
EUR 486
Description: For quantitative detection of mouse Adiponectin in cell culture supernates, serum, plasma(heparin, EDTA) and urine.

Mouse AXL PicoKine ELISA Kit

EK0660 96 wells
EUR 425
Description: For quantitative detection of mouse AXL in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse BAFF PicoKine ELISA Kit

EK0664 96 wells
EUR 456
Description: For quantitative detection of mouse BAFF in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse CCL28 PicoKine ELISA Kit

EK0691 96 wells
EUR 425
Description: For quantitative detection of mouse CCL28 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse Osteoactivin/GPNMB PicoKine ELISA Kit