GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells

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GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells

Background: A serious problem for the medical use of human pluripotent stem cells is the event of secure, sturdy and managed differentiation protocols. Adaptation of analysis protocols utilizing reagents designated as research-only to these that are appropriate for medical use, also known as good manufacturing follow (GMP) reagents, is an important and laborious step within the translational pipeline. Nonetheless, revealed protocols to help this course of stay very restricted.

Strategies: We tailored research-grade protocols for the derivation and differentiation of long-term neuroepithelial stem cell progenitors (lt-NES) to GMP-grade reagents and elements appropriate for medical functions. We screened the robustness of the protocol with six clinical-grade hESC traces deposited within the UK Stem Cell Financial institution.

Outcomes: Right here, we current a brand new GMP-compliant protocol to derive lt-NES, that are multipotent, bankable and karyotypically steady. This protocol resulted in sturdy and reproducible differentiation of a number of clinical-grade embryonic stem cells from which we derived lt-NES. Moreover, GMP-derived lt-NES demonstrated a excessive neurogenic potential whereas retaining the flexibility to be redirected to a number of neuronal sub-types.

Conclusions: Total, we report the feasibility of derivation and differentiation of clinical-grade embryonic stem cell traces into lt-NES beneath GMP-compliant circumstances. Our protocols may very well be used as a versatile software to hurry up translation-to-clinic of pluripotent stem cells for a wide range of neurological therapies or regenerative medication research.

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Individual Reaction Mix 5
G065-5 200 reactions
EUR 200.4

Individual Reaction Mix
G065-X 200 reactions
EUR 200.4

Individual Reaction Mix 1
G065-1 200 reactions
EUR 200.4

Individual Reaction Mix 10
G065-10 200 reactions
EUR 200.4

Individual Reaction Mix 11
G065-11 200 reactions
EUR 200.4

Individual Reaction Mix 12
G065-12 200 reactions
EUR 200.4

Individual Reaction Mix 2
G065-2 200 reactions
EUR 200.4

Individual Reaction Mix 3
G065-3 200 reactions
EUR 200.4

Individual Reaction Mix 4
G065-4 200 reactions
EUR 200.4

Individual Reaction Mix 6
G065-6 200 reactions
EUR 200.4

Individual Reaction Mix 7
G065-7 200 reactions
EUR 200.4

Individual Reaction Mix 8
G065-8 200 reactions
EUR 200.4

Individual Reaction Mix 9
G065-9 200 reactions
EUR 200.4

5 Component Mix
AOAC-MIX-1 EACH
EUR 117.42

Volatile Organics Mix
60-BIG-MIX 1ML
EUR 120.84

Semi-volatile Organics Mix
76-BIG-MIX 1ML
EUR 150.48

Volatile Organics Mix (76 Components)
8260-BIG-MIX 1ML
EUR 296.4

Pesticide Mix 5 Containing 14 Compounds in Acetonitrile
SPXPR-5 1ML
EUR 183.54

Volatile Organics Mix (Low Level)
60-BIG-MIX-200 1ML
EUR 116.28

Volatile Organics Mix (High Level)
60-BIG-MIX-2000 1ML
EUR 165.3

Canadian Pesticide Mix 5 Containing 26 Compounds
CAN-CAN-5 1ML
EUR 127.68

2X PCR Pre-Mix (EF) (Reaction Volume 30ul) (96 Tubes)
9K-002-0001 96tubes, 96prep
EUR 373.2

2X PCR Pre-Mix (EF) (Reaction Volume 30ul) (576 Tubes)
9K-002-0002 576tubes, 576prep
EUR 1391.1

Individual Standard Mix A for 3/90 and 7/91 SOW
CLPP-A90 1ML
EUR 102.6

amfiEco PCR Master Mix,8-Strip RTU(2X), for 50ul reaction
P0704-096 96 rxns
EUR 174

ICP Multi Elem (18) Std 5% HNO3
ICP18-MIX-2 1L
EUR 1687.2

HICAL Acids Mix 5mL
HICAL-ACIDS-5 5ML
EUR 272.46

IC Multi Elem (5) Cation Std in H2O
ICC5-MIX-THG 100ML
EUR 148.2

Genorise® 5 x Polymerase Mix
GR-108010 8 x 1.5 mL
EUR 597.6

5 Component Mix in Dimethyl Sulfoxide
USP-RS-C1 1ML
EUR 41.04

Reaction Columns 2ml
CHR5348 PK100
EUR 175.56

2X Reaction Buffer
1068-20 each
EUR 222

2X Reaction Buffer
1068-80 each
EUR 352.8

IDO1 Reaction Solution
73001 10 ml
EUR 205
Description: IDO1 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).

IDO2 Reaction Solution
73003 10 ml
EUR 205
Description: IDO2 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO2-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO2 Inhibitor Screening Assay Kit (BPS Cat. #72022) and/or with purified, active IDO2, His-tag (BPS Cat. #71194) in combination with 1x IDO2 Assay Buffer (BPS Cat. #73004).

TDO Reaction Solution
73005 10 ml
EUR 205
Description: TDO Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for TDO-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS TDO Inhibitor Screening Assay Kit (BPS Cat. #72023) and/or with purified, active TDO, His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).

0.2ml Individual PCR Tubes
PCR1178 PK1000
EUR 44.35

0.2ml Individual PCR Tubes
PCR1186 PK1000
EUR 43.66

2×Taq PCR Master Mix(with dye)
K1034-5 5×1 ml
EUR 142.8

Benzodiazepine (Oxazepam)-BSA Antigen (HM238) (Molar Reaction Ratio: 5:1)
VAng-Cr3654-1mg 1 mg
EUR 472.8
Description: Benzodiazepine (Oxazepam)-BSA Antigen, matched pairs: HM238(detection); Molar Reaction Ratio: 5:1 (Benzodiazepine:BSA); Used for Lateral Flow.

RANGER Reaction Buffer, 5x
BIO-37114 3 x 1.25ml Ask for price

MyFi Reaction Buffer, 5x
BIO-37115 3 x 1.25ml Ask for price

amfiXpand 2x Reaction Buffer
P0333-001 1ml
EUR 121.2

amfiFusion 2x Reaction Buffer
P0343-001 1ml
EUR 124.8

Templiphi 2000 Reaction Kit
28964286 EACH
EUR 3735.78

IDO1 Fluorogenic Reaction Solution
73009 10 ml
EUR 205
Description: IDO1 Fluorogenic Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (BPS Cat. #72037 &Cat. #72047) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).

TDO Fluorogenic Reaction Solution
73010 10 ml
EUR 205
Description: TDO Fluorogenic Reaction Solution is an optimized, proprietary_x000D_formulation containing all the necessary reaction components for TDO-catalyzed_x000D_conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays._x000D_This product is intended to be used with the BPS Human TDO Fluorogenic Inhibitor_x000D_Screening Assay Kits (BPS Cat. #72039 & Cat. #72049) and/or with purified, active TDO,_x000D_His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).

IL-8 (-5 to +5)
5-01377 4 x 5mg Ask for price

Pipette 10ml Individual Wrap Corning
4101 PK200
EUR 80.94

Extra T7 gRNA PCR primer mix (5 uM)
CAS510A-PR 50 assays
EUR 183.6

Forward and Reverse UCR1 Primer Mix 5 ?M
LV961A-UCR1 50 ul
EUR 198

2',3',5'-triacetyl-5-Azacytidine
C4119-5 5 mg
EUR 141.6
Description: 2',3',5'-triacetyl-5-Azacytidine (TAC) is the lead prodrug form of 5-azacytidine which may be rapidly absorbed after oral administration [1]. 5-Azacytidine is an inhibitor of DNA methyltransferase [2].

2',3',5'-triacetyl-5-Azacytidine
B2822-5 each
EUR 183.6

Histatin 5
5-01307 4 x 1mg Ask for price

5-Iodotubercidin
A3125-5 5 mg
EUR 201.6
Description: 5-Iodotubercidin (Itu) is a purine derivative and hence an inhibitor of adenosine kinase with an IC50 value of 26 nM [1]. Adenosine kinase is important in regulating the intracellular and extracellular concentrations of adenosine and hence diverse physiological actions of adenosine [2].

5-ROX
B8212-5 5 mg
EUR 234

GNF-5
B1329-5 each
EUR 170.4

Aftin-5
2575-5 each
EUR 548.4

CHD-5
2693-5 each
EUR 183.6

Necrostatin-5
1865-5 each
EUR 151.2

Hi-Fi Reaction Buffer, 5x
BIO-37110 2 x 1.5ml Ask for price

MyTaq reaction Buffer Colourless, 5x
BIO-37111 4 x 1ml Ask for price

MyTaq Reaction Buffer Red, 5x
BIO-37112 4 x 1ml Ask for price

amfiEco Taq Reaction Buffer(2X)
P0703-001 1ml
EUR 100.8

amfiEco Taq Reaction Buffer(2X)
P0703-005 5ml
EUR 213.6

Kinase Reaction Buffer Concentrate, 60ML
X104-60ML 60ML
EUR 146.4

Electrothermal RS600 STEM reaction block
HEA5500 EACH
EUR 8360.76

Electrothermal RS1000 STEM reaction block
HEA5504 EACH
EUR 4574.82

Mix 524.3 Mix B 69 Components
5243-VCM 1ML
EUR 404.7

PCR Mix
L5051100 2.5 ml
EUR 128.4
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
G010 250 ul 10 mM each
EUR 87.6

dNTP Mix
G128 500 ul 10 mM each
EUR 98.4

dNTP Mix
G129 1.0 ml 10 mM each
EUR 121.2

NTP Mix
G943 250 ul 25 mM each
EUR 93.6

NTP Mix
G944 500 ul 25 mM each
EUR 116.4

NTP Mix
G945 1.0 ml 25 mM each
EUR 156

dNTP Mix
K6011105-100 100 ul (10 mM each)
EUR 103.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-1000 1000 ul (10 mM each)
EUR 241.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-200 200 ul (10 mM each)
EUR 111.6
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-400 400 ul (10 mM each)
EUR 139.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Analyte Mix
5031-A 1ML
EUR 166.44

Analyte Mix
5491-A 1ML
EUR 45.6

Benzidines Mix
605-X-MC 1ML
EUR 42.18

Analyte Mix
608-A 1ML
EUR 67.26

Alcohols Mix
8015B-A 1ML
EUR 44.46

Analyte Mix
8140-A 1ML
EUR 165.3

Analyte Mix
8141-AB 1ML
EUR 182.4

Phenolics Mix
CLPS-A 1ML
EUR 46.74

Phenol 5 Comp Mix Std 2000ug/mL in MeOH
REPHE004 1ML
EUR 79.8

Phenol 5 Comp Mix Std 2000ug/mL in DCM
REPHE008 1ML
EUR 79.8

Phenol 5 Comp Mix Std 2000ug/mL in MeOH
REPHE042 1ML
EUR 80.94

Phenol 5 Comp Mix Std Mixed Conc in MeOH
REPHE044 1ML
EUR 80.94

Phenol 5 Comp Mix Std 2000ug/mL in DCM
REPHE045 1ML
EUR 80.94

Phenol 5 Comp Mix Std 2000ug/mL in DCM
REPHE046 1ML
EUR 80.94

VOC Std 5 Comp Mix 100ug/mL in MeOH
REVOC0043 1ML
EUR 115.14

VOC Std 5 Comp Mix Mixed Concs in MeOH
REVOC0044 1ML
EUR 38.76

VOC Std 5 Comp Mix Mixed Concs in MeOH
REVOC0045 1ML
EUR 62.7

Accuris High Fidelity PCR Master Mix, sample, 5 rxns
PR1001-HF-S 1 each
EUR 7.1

BD 6intransfer pipette1and2ml graduationssterile Individual wrap
357575 PK500
EUR 118.56

Thrombin Receptor Activator for Peptide 5 (TRAP-5)
A1036-5 5 mg
EUR 122.4
Description: Thrombin Receptor Activator for Peptide 5 (TRAP-5),(C30H50N8O7), a peptide with the sequence NH2-Ser-Phe-Leu-Leu-Arg-COOH, MW= 634.76. coagulation factor II (thrombin) receptor is a G protein-coupled receptor involved in the regulation of thrombotic response.

Dynamic Laser Speckle Imaging meets Machine Studying to allow Fast Antibacterial Susceptibility Testing (DyRAST)

Fast antibacterial susceptibility testing (RAST) strategies which measure change of a bacterial phenotype in response to a given therapy are of great significance in healthcare, as they’ll help care-givers within the well timed administration of appropriate remedies. Numerous RAST strategies have been reported for monitoring bacterial phenotypes, together with dimension, form, movement, and redox state. Nonetheless, they nonetheless require cumbersome and costly devices – which hinders their software in resource-limited environments – and/or make the most of labeling reagents which may intervene with antibiotics and add to price.

Moreover, the present RAST strategies don’t deal with the potential gradual adaptation of micro organism to antibiotics, which may result in a false prognosis. On this work, we current a RAST strategy by leveraging machine studying to research time-resolved dynamic laser speckle imaging (DLSI) outcomes. DLSI captures change of bacterial movement/division in response to antibiotic remedies.
Our technique precisely predicts the minimal inhibitory focus (MIC) of ampicillin and gentamicin for a mannequin pressure of Escherichia coli (E. coli Ok-12) in 60 minutes, in comparison with 6 hours utilizing the at the moment FDA-approved phenotype-based RAST method. Along with ampicillin (a β-lactam) and gentamicin (an aminoglycoside), we studied the impact of ceftriaxone (a third-generation medical cephalosporin) on E. coli Ok-12. The machine studying algorithm was skilled and validated utilizing the in a single day outcomes of a gold customary AST technique enabling prediction of MIC with a equally excessive accuracy, but considerably sooner.

Polymer-Supported Phosphoric, Phosphonic and Phosphinic Acids-From Synthesis to Properties and Purposes in Separation Processes

Environment friendly separation applied sciences are essential to the atmosphere and world financial system. The problem posed to scientists is how one can engineer selectivity in the direction of a focused substrate, particularly from multicomponent options. Polymer-supported reagents have gained plenty of consideration on this context, as they eradicate plenty of inconveniences regarding broadly used solvent extraction strategies.

However, the selection of an applicable ligand for immobilization could also be derived from the habits of soluble compounds beneath solvent extraction circumstances. Organophosphorus compounds play a big function in separation science and expertise. The options they possess, equivalent to variable oxidation states, multivalence, asymmetry and metal-binding properties, spotlight their standing as a novel and versatile class of compounds, able to selective separations continuing by means of completely different mechanisms.

This evaluate supplies an in depth survey of polymers containing phosphoric, phosphonic and phosphinic acid functionalities within the aspect chain and covers foremost advances within the preparation and software of those supplies in separation science, together with essentially the most related synthesis routes (Arbuzov, Perkow, Mannich, Kabachnik-Fields reactions, and many others.), in addition to the primary levels within the improvement of organophosphorus resins and a very powerful achievements within the subject.

Individual Reaction Mix 7
G065-7 200 reactions
EUR 200.4

Individual Reaction Mix 8
G065-8 200 reactions
EUR 200.4

Individual Reaction Mix 9
G065-9 200 reactions
EUR 200.4

Volatile Organics Mix
60-BIG-MIX 1ML
EUR 120.84

5 Component Mix
AOAC-MIX-1 EACH
EUR 117.42

Pesticide Mix 4 Containing 15 Compounds in Acetonitrile
SPXPR-4 1ML
EUR 175.56

Semi-volatile Organics Mix
76-BIG-MIX 1ML
EUR 150.48

Canadian Pesticide Mix 4 Containing 19 Compounds
CAN-CAN-4 1ML
EUR 123.12

Volatile Organics Mix (76 Components)
8260-BIG-MIX 1ML
EUR 296.4

Volatile Organics Mix (Low Level)
60-BIG-MIX-200 1ML
EUR 116.28

Volatile Organics Mix (High Level)
60-BIG-MIX-2000 1ML
EUR 165.3

2X PCR Pre-Mix (EF) (Reaction Volume 30ul) (96 Tubes)
9K-002-0001 96tubes, 96prep
EUR 373.2

2X PCR Pre-Mix (EF) (Reaction Volume 30ul) (576 Tubes)
9K-002-0002 576tubes, 576prep
EUR 1391.1

Individual Standard Mix A for 3/90 and 7/91 SOW
CLPP-A90 1ML
EUR 102.6

amfiEco PCR Master Mix,8-Strip RTU(2X), for 50ul reaction
P0704-096 96 rxns
EUR 174

40mM dNTP Mix (10mM/80µm each)
PR3040-M-4 1 PC
EUR 190.93

Method 524.2 Revision 4 Mix
5242-R4200 1ML
EUR 76.38

10 mM dNTP Mix of 2.5 mM 4 dNTP Mix
GR103045 1 mL
EUR 75.6

IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4 Regular: 10ug
EUR 380.4
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Reaction Columns 2ml
CHR5348 PK100
EUR 175.56

2X Reaction Buffer
1068-20 each
EUR 222

2X Reaction Buffer
1068-80 each
EUR 352.8

IDO1 Reaction Solution
73001 10 ml
EUR 205
Description: IDO1 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).

IDO2 Reaction Solution
73003 10 ml
EUR 205
Description: IDO2 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO2-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO2 Inhibitor Screening Assay Kit (BPS Cat. #72022) and/or with purified, active IDO2, His-tag (BPS Cat. #71194) in combination with 1x IDO2 Assay Buffer (BPS Cat. #73004).

TDO Reaction Solution
73005 10 ml
EUR 205
Description: TDO Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for TDO-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS TDO Inhibitor Screening Assay Kit (BPS Cat. #72023) and/or with purified, active TDO, His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).

0.2ml Individual PCR Tubes
PCR1178 PK1000
EUR 44.35

0.2ml Individual PCR Tubes
PCR1186 PK1000
EUR 43.66

Feline IL-4 Recombinant Protein
R00230-4 5ug/vial
EUR 310.8
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

pLenti-CLDN1 shRNA-4 Plasmid
PVTBAV04867-4 2 ug
EUR 427.2

Digital Shaker For 4 Microplates
6782-4 EACH
EUR 1110.36

Method 524.2 Revision 4 Mix (High Level)
5242-R4 1ML
EUR 83.22

Volatile Organics Combination Mix D 4 pack
624-DH 1ML
EUR 36.48

RANGER Reaction Buffer, 5x
BIO-37114 3 x 1.25ml Ask for price

MyFi Reaction Buffer, 5x
BIO-37115 3 x 1.25ml Ask for price

amfiXpand 2x Reaction Buffer
P0333-001 1ml
EUR 121.2

amfiFusion 2x Reaction Buffer
P0343-001 1ml
EUR 124.8

Templiphi 2000 Reaction Kit
28964286 EACH
EUR 3735.78

IDO1 Fluorogenic Reaction Solution
73009 10 ml
EUR 205
Description: IDO1 Fluorogenic Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (BPS Cat. #72037 &Cat. #72047) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).

TDO Fluorogenic Reaction Solution
73010 10 ml
EUR 205
Description: TDO Fluorogenic Reaction Solution is an optimized, proprietary_x000D_formulation containing all the necessary reaction components for TDO-catalyzed_x000D_conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays._x000D_This product is intended to be used with the BPS Human TDO Fluorogenic Inhibitor_x000D_Screening Assay Kits (BPS Cat. #72039 & Cat. #72049) and/or with purified, active TDO,_x000D_His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).

DIGITAL SHAKER FOR 4 MICROPLATES, 120V
6780-4 1/pk
EUR 957.6
Description: Lab Equipment; Shakers & Mixers

Mouse FibrOut 4, for brain, neural
4-20507 1 ml Ask for price

Mouse FibrOut 4, for brain, neural
4-20508 5 x 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20533 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20534 5 x 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21553 5 x 1 ml Ask for price

Recombinant Human 4-1BB Receptor Protein
PROTQ07011-4 20ug
EUR 380.4
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein
PROTP02776-4 20ug
EUR 380.4
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

ICP-MS Multi-Element Solution 4
CLMS-4 125ML
EUR 221.16

Pipette 10ml Individual Wrap Corning
4101 PK200
EUR 80.94

Bone Dissociation System 4 (Osteoblasts), Adult Mouse
4-20214 ea Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat
4-20304 ea Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse
4-20404 ea Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat
4-20444 ea Ask for price

Base/Neutral Surrogate Mix (4) (1000ppm) - 5.5mL Bottle
ECS-N-022 5.5ML
EUR 66.12

Acid Extractables Surrogate Mix (4) (2000ppm) - 5.5mL Bottle
ECS-N-023 5.5ML
EUR 98.04

Base/Neutral Surrogate Mix 4 component-10.5mL Bottle
ECS-Z-022 10.5ML
EUR 118.56

Acid Extractables Surrogate Mix 4 component-10.5mL Bottle
ECS-Z-023 10.5ML
EUR 186.96

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG
6781-4 1/pk
EUR 957.6
Description: Lab Equipment; Shakers & Mixers

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat
4-20234 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse
4-20324 ea Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat
4-20374 ea Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat
4-20434 ea Ask for price

Hi-Fi Reaction Buffer, 5x
BIO-37110 2 x 1.5ml Ask for price

MyTaq reaction Buffer Colourless, 5x
BIO-37111 4 x 1ml Ask for price

MyTaq Reaction Buffer Red, 5x
BIO-37112 4 x 1ml Ask for price

amfiEco Taq Reaction Buffer(2X)
P0703-001 1ml
EUR 100.8

amfiEco Taq Reaction Buffer(2X)
P0703-005 5ml
EUR 213.6

Kinase Reaction Buffer Concentrate, 60ML
X104-60ML 60ML
EUR 146.4

Electrothermal RS600 STEM reaction block
HEA5500 EACH
EUR 8360.76

Electrothermal RS1000 STEM reaction block
HEA5504 EACH
EUR 4574.82

Mix 524.3 Mix B 69 Components
5243-VCM 1ML
EUR 404.7

Adipose/Fat Dissociation System 4 (Predipocytes), Mouse and Rat
4-20194 ea Ask for price

Brain Dissociation System 4 (Endothelial, Microvessels), Mouse and Rat
4-20224 ea Ask for price

Endothelial Dissociation System 4 (Endothelial,Cerebral), Mouse and Rat
4-20244 ea Ask for price

Heart Dissociation System 4 (Myocytes,Ventricles), Mouse and Rat
4-20274 ea Ask for price

Muscle Dissociation System 4 (Smooth muscle), Mouse and Rat
4-20334 ea Ask for price

Parotid Dissociation System 4 (Parotid acinar), Mouse and Rat
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PCR Mix
L5051100 2.5 ml
EUR 128.4
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
G010 250 ul 10 mM each
EUR 87.6

dNTP Mix
G128 500 ul 10 mM each
EUR 98.4

dNTP Mix
G129 1.0 ml 10 mM each
EUR 121.2

NTP Mix
G943 250 ul 25 mM each
EUR 93.6

NTP Mix
G944 500 ul 25 mM each
EUR 116.4

NTP Mix
G945 1.0 ml 25 mM each
EUR 156

dNTP Mix
K6011105-100 100 ul (10 mM each)
EUR 103.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-1000 1000 ul (10 mM each)
EUR 241.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-200 200 ul (10 mM each)
EUR 111.6
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix
K6011105-400 400 ul (10 mM each)
EUR 139.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Analyte Mix
5031-A 1ML
EUR 166.44

Analyte Mix
5491-A 1ML
EUR 45.6

Benzidines Mix
605-X-MC 1ML
EUR 42.18

Analyte Mix
608-A 1ML
EUR 67.26

Alcohols Mix
8015B-A 1ML
EUR 44.46

Analyte Mix
8140-A 1ML
EUR 165.3

Analyte Mix
8141-AB 1ML
EUR 182.4

Phenolics Mix
CLPS-A 1ML
EUR 46.74

BD 6intransfer pipette1and2ml graduationssterile Individual wrap
357575 PK500
EUR 118.56

Epithelial Dissociation System 4 (Epithelial,Submandibular salivary), Mouse and Rat
4-20254 ea Ask for price

Heart Dissociation System 4 (Retinal pigment epithelial), Mouse and Rat
4-20294 ea Ask for price

Lung Dissociation System 4 (Alveolar type II), Mouse and Rat
4-20314 ea Ask for price

Reproductive Tissue Dissociation System 4 (Epithelial, vagina), Mouse and Rat
4-20414 ea Ask for price

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 4 vials)
M1040-4 each
EUR 1090.8

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 4 vials)
M1041-4 each
EUR 1364.4

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 4 vials)
M1042-4 each
EUR 1090.8

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 4 vials)
M1043-4 each
EUR 1358.4

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 4 vials)
M1044-4 each
EUR 1090.8

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 4 vials)
M1045-4 each
EUR 1364.4

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 4 vials)
M1046-4 each
EUR 1096.8

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 4 vials)
M1047-4 each
EUR 1364.4

ExoStd? Lyophilized Exosome Standard (30 µg, U87 MG, 4 vials)
M1054-4 each
EUR 1096.8

ExoStd? Lyophilized Exosome Standard (100 µg, U87 MG, 4 vials)
M1055-4 each
EUR 1370.4

Turbidity Std Ratio 4 NTU
CRSR-4-500 500ML
EUR 181.26

ICP-MS Tuning Solution 4
CL-TUNE-4 125ML
EUR 126.54

Adrenal Dissociation System 4 (Heart, Adrenal chromaffin, Paraneurons), Mouse and Rat
4-20204 ea Ask for price

Kidney Dissociation System 4 (Inner medullary duct,Papillae), Mouse and Rat
4-29294 ea Ask for price

ExoStd? Lyophilized Exosome Standard (30 µg, COLO1 cell line, 4 vials)
M1048-4 each
EUR 1096.8

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