Description: A sandwich quantitative ELISA assay kit for detection of Human Kallikrein 1 (KLK1) in samples from serum, plasma or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Kallikrein 1 (KLK1) in samples from serum, plasma or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Kallikrein 1 (KLK1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Kallikrein 1 (KLK1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Description: Description of target: Kallikrein-1, also known as tissue kallikrein, is a protein that in humans is encoded by the KLK1 gene. This serine protease generates Lys-bradykinin by specific proteolysis of kininogen-1. KLK1 is a member of the peptidase S1 family. Its gene is mapped to 19q13.3. In all, it has got 262-amino acids which contain a putative signal peptide, followed by a short activating peptide and the protease domain. The protein is mainly found in kidney, pancreas, and salivary gland, showing a unique pattern of tissue-specific expression relative to other members of the family. KLK1 is implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <12pg/ml

Description: Description of target: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. Mice lacking the encoded protein are unable to generate significant levels of kinins in most tissues, develop cardiovascular abnormalities and exhibit hypercalciuria of renal origin. This gene is located in a cluster of several related kallikrein genes on chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 13.4 pg/mL

Description: Description of target: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.083 ng/mL

Description: Description of target: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. Mice lacking the encoded protein are unable to generate significant levels of kinins in most tissues, develop cardiovascular abnormalities and exhibit hypercalciuria of renal origin. This gene is located in a cluster of several related kallikrein genes on chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 13.4pg/mL

Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse KLK1 in samples from serum, plasma, tissue homogenates and other biological fluids.