Human NOTCH1 PicoKine ELISA Kit

Human NOTCH1 PicoKine ELISA Kit 

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ELISA kit for Human NOTCH1

EK5779 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human NOTCH1 in samples from serum, plasma, tissue homogenates and other biological fluids.

NOTCH1 ELISA Kit (Human) (OKAN04864)

OKAN04864 96 Wells
EUR 792
Description: Description of target: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.055 ng/mL

NOTCH1 ELISA Kit (Human) (OKBB01133)

OKBB01133 96 Wells
EUR 544
Description: Description of target: Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated (NOTCH1), is a human gene encoding a single-pass transmembrane receptor. It functions as a receptor for membrane bound ligands, and may play multiple roles during development. NOTCH1 may normally coordinates the process of somitogenesis, and the activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <12pg/ml

NOTCH1 ELISA Kit (Human) (OKCD08985)

OKCD08985 96 Wells
EUR 975
Description: Description of target: NOTCH1 is a member of the Notch family. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.062ng/mL

Hamster Notch1 ELISA Kit

QY-E90124 96T
EUR 478

Notch1

RA19069 100 ul
EUR 331

NOTCH1 ELISA Kit (Mouse) (OKCD02917)

OKCD02917 96 Wells
EUR 857
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.054 ng/mL

NOTCH1 ELISA Kit (Rat) (OKEH06289)

OKEH06289 96 Wells
EUR 662
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39.4 pg/mL

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 202

NOTCH1 ELISA Kit (Human) : 96 Wells (OKEH00479)

OKEH00479 96 Wells
EUR 662
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May be important for normal lymphocyte function. In altered form, may contribute to transformation or progression in some T-cell neoplasms. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. May be important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, may function as a receptor for neuronal DNER and may be involved in the differentiation of Bergmann glia.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 49 pg/mL

Human ADAMTS4 PicoKine ELISA Kit

EK1372 96 wells
EUR 425
Description: For quantitative detection of human ADAMTS4 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human ANGPTL3 PicoKine ELISA Kit

EK1374 96 wells
EUR 425
Description: For quantitative detection of human ANGPTL3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human TGFBR3 PicoKine ELISA Kit

EK1383 96 wells
EUR 425
Description: For quantitative detection of human TGFBR3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human LOXL2 PicoKine ELISA Kit

EK1391 96 wells
EUR 425
Description: For quantitative detection of human LOXL2 in cell culture supernates, cell lysates, serum and plasma(heparin, EDTA).

Human Epiregulin PicoKine ELISA Kit

EK1394 96 wells
EUR 425
Description: For quantitative detection of human Epiregulin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CD97 PicoKine ELISA Kit

EK1402 96 wells
EUR 425
Description: For quantitative detection of human CD97 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human COMT PicoKine ELISA Kit

EK1406 96 wells
EUR 425
Description: For quantitative detection of human COMT in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human NRCAM PicoKine ELISA Kit

EK1408 96 wells
EUR 425
Description: For quantitative detection of human NRCAM in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CD5L PicoKine ELISA Kit

EK1413 96 wells
EUR 425
Description: For quantitative detection of activated human CD5L in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CD44 PicoKine ELISA Kit

EK1418 96 wells
EUR 425
Description: For quantitative detection of human CD44 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CD47 PicoKine ELISA Kit

EK1421 96 wells
EUR 425
Description: For quantitative detection of human CD47 in cell culture supernates and serum.

Human CD28 PicoKine ELISA Kit

EK1429 96 wells
EUR 425
Description: For quantitative detection of human CD28 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human Hepcidin PicoKine ELISA Kit

EK1431 96 wells
EUR 425
Description: For quantitative detection of human Hepcidin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human ADA PicoKine ELISA Kit

EK1446 96 wells
EUR 425
Description: For quantitative detection of human ADA in cell culture supernates, serum and pleural fluid.

Human IDS PicoKine ELISA Kit

EK1452 96 wells
EUR 425
Description: For quantitative detection of human IDS in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human APOE PicoKine ELISA Kit

EK1455 96 wells
EUR 425
Description: For quantitative detection of human APOE in cell culture supernates, serum, plasma(heparin, EDTA), saliva, milk and urine.

Human APOA1 PicoKine ELISA Kit

EK1456 96 wells
EUR 425
Description: For quantitative detection of human APOA1 in cell culture supernates, serum, plasma(heparin, EDTA) and urine.

Human FABP4 PicoKine ELISA Kit

EK1459 96 wells
EUR 425
Description: For quantitative detection of human FABP4 in cell culture supernates, serum, plasma(heparin, EDTA) and cell lysates.

Human Hemopexin PicoKine ELISA Kit

EK1466 96 wells
EUR 425
Description: For quantitative detection of human Hemopexin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human GHR PicoKine ELISA Kit

EK1467 96 wells
EUR 425
Description: For quantitative detection of human GHR in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human HE4 PicoKine ELISA Kit

EK1469 96 wells
EUR 425
Description: For quantitative detection of human HE4 in cell culture supernates, serum, plasma(heparin, EDTA), saliva, urine and human milk.

Human SFRP5 PicoKine ELISA Kit

EK1472 96 wells
EUR 425
Description: For quantitative detection of human SFRP5 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human ADAM15 PicoKine ELISA Kit

EK1484 96 wells
EUR 425
Description: For quantitative detection of human ADAM15 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human Afamin PicoKine ELISA Kit

EK1487 96 wells
EUR 425
Description: For quantitative detection of human Afamin in cell culture supernates, serum and urine.

Human EDIL3 PicoKine ELISA Kit

EK1500 96 wells
EUR 425
Description: For quantitative detection of human EDIL3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human SPHK1 PicoKine ELISA Kit

EK1501 96 wells
EUR 425
Description: For quantitative detection of human SPHK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human LRIG3 PicoKine ELISA Kit

EK1503 96 wells
EUR 425
Description: For quantitative detection of human LRIG3 in cell culture supernates, serum and plasma(heparin).

Human BCHE PicoKine ELISA Kit

EK1507 96 wells
EUR 425
Description: For quantitative detection of human BCHE in cell culture supernates, serum, plasma (heparin, EDTA), saliva, urine and human milk.

Human Persephin PicoKine ELISA Kit

EK1509 96 wells
EUR 425
Description: For quantitative detection of human Persephin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human TREML1 PicoKine ELISA Kit

EK1521 96 wells
EUR 425
Description: For quantitative detection of human TREML1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human WIF1 PicoKine ELISA Kit

EK1524 96 wells
EUR 425
Description: For quantitative detection of human WIF1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CD48 PicoKine ELISA Kit

EK1527 96 wells
EUR 425
Description: For quantitative detection of human CD48 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human ICAM5 PicoKine ELISA Kit

EK1529 96 wells
EUR 425
Description: For quantitative detection of human ICAM5 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human GREM2 PicoKine ELISA Kit

EK1533 96 wells
EUR 425
Description: For quantitative detection of human GREM2 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human Artemin PicoKine ELISA Kit

EK1534 96 wells
EUR 425
Description: For Quantitative Detection of human Artemin in cell culture supernates, serum and plasma (heparin, EDTA).

Human NOTCH1 PicoKine ELISA Kit