Human NOTCH1 PicoKine ELISA Kit

Human NOTCH1 PicoKine ELISA Kit 

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ELISA kit for Human NOTCH1

EK5779 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human NOTCH1 in samples from serum, plasma, tissue homogenates and other biological fluids.

NOTCH1 ELISA Kit (Human) (OKAN04864)

OKAN04864 96 Wells
EUR 792
Description: Description of target: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.055 ng/mL

NOTCH1 ELISA Kit (Human) (OKBB01133)

OKBB01133 96 Wells
EUR 544
Description: Description of target: Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated (NOTCH1), is a human gene encoding a single-pass transmembrane receptor. It functions as a receptor for membrane bound ligands, and may play multiple roles during development. NOTCH1 may normally coordinates the process of somitogenesis, and the activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <12pg/ml

NOTCH1 ELISA Kit (Human) (OKCD08985)

OKCD08985 96 Wells
EUR 975
Description: Description of target: NOTCH1 is a member of the Notch family. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.062ng/mL

Hamster Notch1 ELISA Kit

QY-E90124 96T
EUR 478

Notch1

RA19069 100 ul
EUR 331

NOTCH1 ELISA Kit (Mouse) (OKCD02917)

OKCD02917 96 Wells
EUR 857
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.054 ng/mL

NOTCH1 ELISA Kit (Rat) (OKEH06289)

OKEH06289 96 Wells
EUR 662
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39.4 pg/mL

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 202

NOTCH1 ELISA Kit (Human) : 96 Wells (OKEH00479)

OKEH00479 96 Wells
EUR 662
Description: Description of target: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May be important for normal lymphocyte function. In altered form, may contribute to transformation or progression in some T-cell neoplasms. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. May be important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, may function as a receptor for neuronal DNER and may be involved in the differentiation of Bergmann glia.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 49 pg/mL

Human ULBP1 PicoKine ELISA Kit

EK1685 96 wells
EUR 425
Description: For quantitative detection of human ULBP1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human ULBP3 PicoKine ELISA Kit

EK1686 96 wells
EUR 425
Description: For quantitative detection of human ULBP3 in cell culture supernates, serum and plasma (heparin, EDTA).

Human Klotho PicoKine ELISA Kit

EK1688 96 wells
EUR 425
Description: For quantitative detection of human Klotho in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human B2M PicoKine ELISA Kit

EK1691 96 wells
EUR 425
Description: For quantitative detection of human B2M in cell culture supernates, serum, plasma (heparin, EDTA), saliva, urine and human milk.

Human Haptoglobin PicoKine ELISA Kit

EK1702 96 wells
EUR 455
Description: For quantitative detection of human Haptoglobin in cell culture supernates, serum and plasma (heparin, EDTA).

Human FGFBP1 PicoKine ELISA Kit

EK1706 96 wells
EUR 425
Description: For quantitative detection of human FGFBP1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human PROS1 PicoKine ELISA Kit

EK1739 96 wells
EUR 425
Description: For quantitative detection of human PROS1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human ckmm PicoKine ELISA Kit

EK1751 96 wells
EUR 425
Description: For quantitative detection of human ckmm in cell culture supernates, serum and plasma (heparin, EDTA).

Human ROBO1 PicoKine ELISA Kit

EK1755 96 wells
EUR 425
Description: For quantitative detection of human ROBO1 in cell culture supernates, serum and plasma (heparin).

Human Ki67 PicoKine ELISA Kit

EK1759 96 wells
EUR 455
Description: For quantitative detection of human Ki67 in cell culture supernates, serum and plasma (heparin, EDTA).

Human PAM PicoKine ELISA Kit

EK1765 96 wells
EUR 425
Description: For quantitative detection of human PAM in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Human TINAGL1 PicoKine ELISA Kit

EK1766 96 wells
EUR 425
Description: For quantitative detection of human TINAGL1 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Human CPA1 PicoKine ELISA Kit

EK1770 96 wells
EUR 425
Description: For quantitative detection of human CPA1 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Human EphA1 PicoKine ELISA Kit

EK1796 96 wells
EUR 425
Description: For quantitative detection of human EphA1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human EphA2 PicoKine ELISA Kit

EK1797 96 wells
EUR 425
Description: For quantitative detection of human EphA2 in cell culture supernates, serum and plasma (heparin, EDTA).

Human CD164 PicoKine ELISA Kit

EK1811 96 wells
EUR 425
Description: For quantitative detection of human CD164 in cell culture supernates, serum and plasma (heparin, EDTA).

Human REG1A PicoKine ELISA Kit

EK1812 96 wells
EUR 425
Description: For quantitative detection of human REG1A in cell culture supernates, serum and plasma (heparin).

Human CES1 PicoKine ELISA Kit

EK1813 96 wells
EUR 425
Description: For quantitative detection of human CES1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human CES2 PicoKine ELISA Kit

EK1814 96 wells
EUR 425
Description: For quantitative detection of human CES2 in cell culture supernates, serum and plasma (heparin, EDTA).

Human REG3A PicoKine ELISA Kit

EK1834 96 wells
EUR 425
Description: For quantitative detection of human REG3A in cell culture supernates, serum and plasma (heparin).

Human LYPD3 PicoKine ELISA Kit

EK1837 96 wells
EUR 425
Description: For quantitative detection of human LYPD3 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Human MANF PicoKine ELISA Kit

EK1845 96 wells
EUR 425
Description: For quantitative detection of human MANF in cell culture supernates, serum and plasma (heparin, EDTA).

Human CD200R1 PicoKine ELISA Kit

EK1850 96 wells
EUR 425
Description: For quantitative detection of human CD200R1 in cell culture supernates, serum and plasma (heparin, EDTA).

Human EDAR PicoKine ELISA Kit

EK1851 96 wells
EUR 425
Description: For quantitative detection of human EDAR in cell culture supernates, serum and plasma (heparin, EDTA).

Human Brorin PicoKine ELISA Kit

EK1852 96 wells
EUR 425
Description: For quantitative detection of human Brorin in cell culture supernates, serum and plasma (heparin, EDTA).

Human EDA PicoKine ELISA Kit

EK1856 96 wells
EUR 425
Description: For quantitative detection of human EDA in cell culture supernates, serum and plasma (heparin, EDTA).

Human TSKU PicoKine ELISA Kit

EK1859 96 wells
EUR 425
Description: For quantitative detection of human TSKU in cell culture supernates, serum and plasma (heparin, EDTA).

Human CPA2 PicoKine ELISA Kit

EK1861 96 wells
EUR 425
Description: For quantitative detection of human CPA2 in cell culture supernates, serum and plasma (heparin, EDTA).

Human SEZ6L PicoKine ELISA Kit

EK1862 96 wells
EUR 425
Description: For quantitative detection of human SEZ6L in cell culture supernates, serum and plasma (heparin).

Human SLITRK1 PicoKine ELISA Kit

EK1866 96 wells
EUR 425
Description: For quantitative detection of human SLITRK1 in cell culture supernates, serum and plasma (heparin).

Human SLITRK2 PicoKine ELISA Kit

EK1867 96 wells
EUR 425
Description: For quantitative detection of human SLITRK2 in cell culture supernates, serum and plasma (heparin).

Human SLITRK6 PicoKine ELISA Kit

EK1868 96 wells
EUR 425
Description: For quantitative detection of human SLITRK6 in cell culture supernates, serum and plasma (heparin).

Human AKR1C3 PicoKine ELISA Kit

EK1869 96 wells
EUR 425
Description: For quantitative detection of human AKR1C3 in cell culture supernates, serum and plasma (heparin, EDTA).

Human AKR1C4 PicoKine ELISA Kit

EK1870 96 wells
EUR 425
Description: For quantitative detection of human AKR1C4 in cell culture supernates, serum and plasma (heparin, EDTA).

Human PAPPA2 PicoKine ELISA Kit

EK1871 96 wells
EUR 425
Description: For quantitative detection of human PAPPA2 in cell culture supernates, serum and plasma (heparin, EDTA).

Human NOTCH1 PicoKine ELISA Kit