Human TIM-3/HAVCR2 PicoKine ELISA Kit

Human TIM-3/HAVCR2 PicoKine ELISA Kit 

To Order Contact us: [email protected]

Human TIM-3/HAVCR2 PicoKine™ Fast ELISA Kit
FEK1644 96 wells
EUR 475
Description: Sandwich High Sensitivity ELISA kit for Quantitative The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detection of Human TIM-3/HAVCR2. 96wells/kit, with removable strips.
Anti-TIM 3/HAVCR2 Antibody
A00657-1 100ug/vial
EUR 294
Human CellExp? TIM-3 / HAVCR2, Cynomolgus Recombinant
P1391-10
EUR 164
Human CellExp? TIM-3 / HAVCR2, Cynomolgus Recombinant
P1391-50
EUR 479
Recombinant Human TIM-3/HAVCR2 (C-Fc-Avi)
CU05-10ug 10ug
EUR 126
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Human TIM-3/HAVCR2 (C-Fc-Avi)
CU05-1mg 1mg
EUR 1318
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Human TIM-3/HAVCR2 (C-Fc-Avi)
CU05-500ug 500ug
EUR 963
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Human TIM-3/HAVCR2 (C-Fc-Avi)
CU05-50ug 50ug
EUR 278
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Polyclonal HAVCR2 / TIM-3 Antibody (aa176-194)
APR03015G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HAVCR2 / TIM-3 (aa176-194). This antibody is tested and proven to work in the following applications:
Recombinant Cynomolgus TIM-3/HAVCR2 (N-His)
CU83-10ug 10ug
EUR 141
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Cynomolgus TIM-3/HAVCR2 (N-His)
CU83-1mg 1mg
EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Cynomolgus TIM-3/HAVCR2 (N-His)
CU83-500ug 500ug
EUR 1186
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Cynomolgus TIM-3/HAVCR2 (N-His)
CU83-50ug 50ug
EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
DLR-HAVCR2-Hu-48T 48T
EUR 517
  • Should the Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
DLR-HAVCR2-Hu-96T 96T
EUR 673
  • Should the Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
RD-HAVCR2-Hu-48Tests 48 Tests
EUR 521
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
RD-HAVCR2-Hu-96Tests 96 Tests
EUR 723
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
RDR-HAVCR2-Hu-48Tests 48 Tests
EUR 544
Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit
RDR-HAVCR2-Hu-96Tests 96 Tests
EUR 756
HAVCR2 ELISA KIT|Human
EF005096 96 Tests
EUR 689
Tim-3, Human Recombinant
P1357-10
EUR 164
Tim-3, Human Recombinant
P1357-50
EUR 523
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
CX71-10ug 10ug
EUR 121
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
CX71-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
CX71-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
CX71-50ug 50ug
EUR 263
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
HAVCR2 ELISA Kit (Human) (OKCD01216)
OKCD01216 96 Wells
EUR 831
Description: Description of target: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand (PubMed:24825777). Regulates macrophage activation (PubMed:11823861). Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance (PubMed:14556005). In CD8+ cells attenuates TCR-induced signaling, specifically by blocking NF-kappaB and NFAT promoter activities resulting in the loss of IL-2 secretion. The function may implicate its association with LCK proposed to impair phosphorylation of TCR subunits, and/or LGALS9-dependent recruitment of PTPRC to the immunological synapse (PubMed:24337741, PubMed:26492563). In contrast, shown to activate TCR-induced signaling in T-cells probably implicating ZAP70, LCP2, LCK and FYN (By similarity). Expressed on Treg cells can inhibit Th17 cell responses (PubMed:24838857). Receptor for LGALS9 (PubMed:16286920, PubMed:24337741). Binding to LGALS9 is believed to result in suppression of T-cell responses; the resulting apoptosis of antigen-specific cells may implicate HAVCR2 phosphorylation and disruption of its association with BAG6. Binding to LGALS9 is proposed to be involved in innate immune response to intracellular pathogens. Expressed on Th1 cells interacts with LGALS9 expressed on Mycobacterium tuberculosis-infected macrophages to stimulate antibactericidal activity including IL-1 beta secretion and to restrict intracellular bacterial growth (By similarity). However, the function as receptor for LGALS9 has been challenged (PubMed:23555261). Also reported to enhance CD8+ T-cell responses to an acute infection such as by Listeria monocytogenes (By similarity). Receptor for phosphatidylserine (PtSer); PtSer-binding is calcium-dependent. May recognize PtSer on apoptotic cells leading to their phagocytosis. Mediates the engulfment of apoptotic cells by dendritic cells. Expressed on T-cells, promotes conjugation but not engulfment of apoptotic cells. Expressed on dendritic cells (DCs) positively regulates innate immune response and in synergy with Toll-like receptors promotes secretion of TNF-alpha. In tumor-imfiltrating DCs suppresses nucleic acid-mediated innate immune repsonse by interaction with HMGB1 and interfering with nucleic acid-sensing and trafficking of nucleid acids to endosomes (By similarity). Expressed on natural killer (NK) cells acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453). In contrast, shown to suppress NK cell-mediated cytotoxicity (PubMed:22383801). Negatively regulates NK cell function in LPS-induced endotoxic shock (By similarity).By similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More…</a></p> Manual assertion inferred from sequence similarity toiUniProtKB:Q8VIM0 (HAVR2_MOUSE)1 Publication <p>Manually curated information which has been inferred by a curator based on his/her scientific knowledge or on the scientific content of an article.</p> <p><a href="/manual/evidences#ECO:0000305">More…</a></p> Manual assertion inferred by curator fromiRef.20"Regulation of T cell responses by the receptor molecule Tim-3."_x005F_x005F_x000D_Gorman J.V., Colgan J.D._x005F_x005F_x000D_Immunol. Res. 59:56-65(2014) [PubMed] [Europe PMC] [Abstract]Cited for: REVIEW ON FUNCTION IN REGULATING T-CELL RESPONSES.7 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease."_x005F_x005F_x000D_Monney L., Sabatos C.A., Gaglia J.L., Ryu A., Waldner H., Chernova T., Manning S., Greenfield E.A., Coyle A.J., Sobel R.A., Freeman G.J., Kuchroo V.K._x005F_x005F_x000D_Nature 415:536-541(2002) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, VARIANT LEU-140, TISSUE SPECIFICITY.Ref.8"Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance."_x005F_x005F_x000D_Sanchez-Fueyo A., Tian J., Picarella D., Domenig C., Zheng X.X., Sabatos C.A., Manlongat N., Bender O., Kamradt T., Kuchroo V.K., Gutierrez-Ramos J.-C., Coyle A.J., Strom T.B._x005F_x005F_x000D_Nat. Immunol. 4:1093-1101(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.9"The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity."_x005F_x005F_x000D_Zhu C., Anderson A.C., Schubart A., Xiong H., Imitola J., Khoury S.J., Zheng X.X., Strom T.B., Kuchroo V.K._x005F_x005F_x000D_Nat. Immunol. 6:1245-1252(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS A RECEPTOR FOR LGALS9.Ref.16"Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9."_x005F_x005F_x000D_Gleason M.K., Lenvik T.R., McCullar V., Felices M., O'Brien M.S., Cooley S.A., Verneris M.R., Cichocki F., Holman C.J., Panoskaltsis-Mortari A., Niki T., Hirashima M., Blazar B.R., Miller J.S._x005F_x005F_x000D_Blood 119:3064-3072(2012) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY.Ref.18"TIM-3 does not act as a receptor for galectin-9."_x005F_x005F_x000D_Leitner J., Rieger A., Pickl W.F., Zlabinger G., Grabmeier-Pfistershammer K., Steinberger P._x005F_x005F_x000D_PLoS Pathog. 9:E1003253-E1003253(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION AS A RECEPTOR FOR LGALS9.Ref.19"Enhanced suppressor function of TIM-3+ FoxP3+ regulatory T cells."_x005F_x005F_x000D_Gautron A.S., Dominguez-Villar M., de Marcken M., Hafler D.A._x005F_x005F_x000D_Eur. J. Immunol. 44:2703-2711(2014) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY.Ref.22"TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway."_x005F_x005F_x000D_Tomkowicz B., Walsh E., Cotty A., Verona R., Sabins N., Kaplan F., Santulli-Marotto S., Chin C.N., Mooney J., Lingham R.B., Naso M., McCabe T._x005F_x005F_x000D_PLoS ONE 10:E0140694-E0140694(2015) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH VAV1; AKT; LCP2; ZAP70; SYK; PIK3R1; FYN; SH3BP2 AND SH2D2A, MUTAGENESIS OF TYR-265 AND TYR-272. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 33 pg/mL
HAVCR2 ELISA Kit (Human) (OKBB01151)
OKBB01151 96 Wells
EUR 505
Description: Description of target: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml
HAVCR2 ELISA Kit (Human) (OKBB01549)
OKBB01549 96 Wells
EUR 570
Description: Description of target: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CK57-10ug 10ug
EUR 110
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CK57-1mg 1mg
EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CK57-500ug 500ug
EUR 1186
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CK57-50ug 50ug
EUR 232
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc)
CM03-10ug 10ug
EUR 126
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc)
CM03-1mg 1mg
EUR 1877
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc)
CM03-500ug 500ug
EUR 1328
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc)
CM03-50ug 50ug
EUR 232
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CM54-10ug 10ug
EUR 126
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CM54-1mg 1mg
EUR 1877
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CM54-500ug 500ug
EUR 1328
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His)
CM54-50ug 50ug
EUR 232
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Tim-3 Antibody
3808-100
EUR 316
Tim-3 Antibody
3808-30T
EUR 146
Human Relaxin 3 PicoKine ELISA Kit
EK1407 96 wells
EUR 425
Description: For quantitative detection of human Relaxin 3 in cell culture supernates, serum and plasma( heparin).
Human Caspase 3 PicoKine ELISA Kit
EK1425 96 wells
EUR 425
Description: For quantitative detection of human Caspase 3 in cell culture supernate sand serum.
Human Matrilin-3 PicoKine ELISA Kit
EK2022 96 wells
EUR 425
Description: For quantitative detection of human Matrilin-3 in cell culture supernates, serum and plasma (heparin, EDTA).
Human IGFBP-3 PicoKine ELISA Kit
EK0386 96 wells
EUR 425
Description: For quantitative detection of human IGFBP-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human IL-3 PicoKine ELISA Kit
EK0402 96 wells
EUR 425
Description: For quantitative detection of human IL-3 in cell culture supernates, serum and plasma( heparin, EDTA, citrate).
Human MMP-3 PicoKine ELISA Kit
EK0461 96 wells
EUR 436
Description: For quantitative detection of human MMP-3 in cell culture supernates, serum and plasma (heparin).
Human Neurotrophin-3 PicoKine ELISA Kit
EK0472 96 wells
EUR 425
Description: For quantitative detection of human Neurotrophin-3 in cell culture supernates and serum.
Human TIMP-3 PicoKine ELISA Kit
EK0523 96 wells
EUR 456
Description: For quantitative detection of human TIMP-3 in cell culture supernates, serum, plasma(heparin , EDTA) and saliva.
Human Kallikrein 3 PicoKine ELISA Kit
EK0816 96 wells
EUR 456
Description: For quantitative detection of Human Kallikrein 3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human ICAM-3 PicoKine ELISA Kit
EK0940 96 wells
EUR 425
Description: For quantitative detection of human ICAM-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human Ficolin-3 PicoKine ELISA Kit
EK1259 96 wells
EUR 425
Description: For quantitative detection of human Ficolin-3 in cell culture supernates, serum and plasma(heparin).
Human DKK-3 PicoKine ELISA Kit
EK1323 96 wells
EUR 425
Description: For quantitative detection of human DKK-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Recombinant Human TIM-3 Protein
RP00069 5 μg
EUR 149
Recombinant Human TIM-3 Protein
RP00234 5 μg
EUR 136
Human Fibulin-3/EFEMP1 PicoKine ELISA Kit
EK1468 96 wells
EUR 425
Description: For quantitative detection of human Fibulin-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human R-Spondin-3 PicoKine ELISA Kit
EK1512 96 wells
EUR 425
Description: For quantitative detection of human R-Spondin-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human Syndecan-3/SDC3 PicoKine ELISA Kit
EK1555 96 wells
EUR 425
Description: For quantitative detection of human Syndecan-3 in cell culture supernates , cell lysates, serum and plasma(heparin, EDTA).
Human Nectin-3/CD113 PicoKine ELISA Kit
EK1961 96 wells
EUR 425
Description: For quantitative detection of human Nectin-3/CD113 in cell culture supernates, serum and plasma (heparin, EDTA).
Human CCL7/MCP-3 PicoKine ELISA Kit
EK0443 96 wells
EUR 425
Description: For quantitative detection of human CCL7 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human Galectin-3/LGALS3 PicoKine ELISA Kit
EK0764 96 wells
EUR 425
Description: For quantitative detection of human Galectin-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Human PTX3/Pentraxin 3 PicoKine ELISA Kit
EK0861 96 wells
EUR 425
Description: For quantitative detection of Human PTX3 in cell culture supernates, serum, plasma(EDTA) and saliva.

Human TIM-3/HAVCR2 PicoKine ELISA Kit